Hepatocellular carcinoma (HCC) presents a significant problem that necessitates a greater understanding of its underlying molecular complexity in order to improve diagnostics and therapies. Recent studies have shed light on the critical role that mitochondrial dysfunction plays in the development and course of HCC. Once thought to be primarily involved in the synthesis of cellular energy, mitochondria are now known to be key participants in the regulation of a variety of cellular functions that go beyond bioenergetics. The purpose of this (...) review is to elucidate the diagnostic and therapeutic implications of mitochondrial dysfunction in HCC by synthesising ideas from conventional and contemporary scientific literature. Within diagnostics, the discovery of mitochondrial biomarkers such as mutations in mitochondrial DNA and abnormalities in respiratory chain complex activities provides a state-of-the-art viewpoint for the timely identification and accurate description of HCC. In addition, non-invasive imaging methods that focus on mitochondrial function offer prospective means of improving clinical diagnostic accuracy. Moving on to treatment, a growing area of study investigates how mitochondria-targeted therapies might be used to treat HCC. Novel substances and repurposed medications with the potential to induce selective apoptosis in cancer cells, reduce oxidative stress, and restore mitochondrial homeostasis are highly promising. In the fight against hepatocellular carcinoma, an understanding of the complex interactions between mitochondrial dysfunction and HCC opens new diagnostic opportunities and paves the way for individualised treatment plans. (shrink)

Online data collection methods are expanding the ease and access of developmental research for researchers and participants alike. While its popularity among developmental scientists has soared during the COVID-19 pandemic, its potential goes beyond just a means for safe, socially distanced data collection. In particular, advances in video conferencing software has enabled researchers to engage in face-to-face interactions with participants from nearly any location at any time. Due to the novelty of these methods, however, many researchers still remain uncertain about (...) the differences in available approaches as well as the validity of online methods more broadly. In this article, we aim to address both issues with a focus on moderated data collected using video-conferencing software. First, we review existing approaches for designing and executing moderated online studies with young children. We also present concrete examples of studies that implemented choice and verbal measures and looking time across both in-person and online moderated data collection methods. Direct comparison of the two methods within each study as well as a meta-analysis of all studies suggest that the results from the two methods are comparable, providing empirical support for the validity of moderated online data collection. Finally, we discuss current limitations of online data collection and possible solutions, as well as its potential to increase the accessibility, diversity, and replicability of developmental science. (shrink)

Data analytics, machine intelligence, and other cognitive algorithms have been employed in predicting various types of diseases in health care. The revolution of artificial neural networks in the medical discipline emerged for data-driven applications, particularly in the healthcare domain. It ranges from diagnosis of various diseases, medical image processing, decision support system, and disease prediction. The intention of conducting the research is to ascertain the impact of parameters on diabetes data to predict whether a particular patient has a disease or (...) not. This paper develops an improved ANN model trained using an artificial backpropagation scaled conjugate gradient neural network algorithm to predict diabetes effectively. For validating the performance of the proposed model, we conduct a large set of experiments on a Pima Indian Diabetes dataset using accuracy and mean squared error as evaluation metrics. We use different number of neurons in the hidden layer, ranging from 5 to 50, to train the ANN models. The experimental results show that the ABP-SCGNN model, containing 20 neurons, attains 93% accuracy on the validation set, which is higher than using the other ANNs models. This result confirms the model’s effectiveness and efficiency in predicting diabetes disease from the required data attributes. (shrink)

This book is a major contribution to decision theory, focusing on the question of when it is rational to accept scientific theories. The author examines both Bayesian decision theory and confirmation theory, refining and elaborating the views of Ramsey and Savage. He argues that the most solid foundation for confirmation theory is to be found in decision theory, and he provides a decision-theoretic derivation of principles for how many probabilities should be revised over time. Professor Maher defines a notion (...) of accepting a hypothesis, and then shows that it is not reducible to probability and that it is needed to deal with some important questions in the philosophy of science. A Bayesian decision-theoretic account of rational acceptance is provided together with a proof of the foundations for this theory. A final chapter shows how this account can be used to cast light on such vexed issues as verisimilitude and scientific realism. (shrink)

The Mycobacterium Tuberculosis complex is a group of species of Mycobacteria involved in a serious bacterial disease which infects the respiratory system and organs. Multi-drug resistant (MDR) strains have been produced as a result of the fast emergence of resistance against first-line anti-tuberculosis medicines in recent years worldwide. The objective of this study is to determine alternatives to anti-mycobacterial antibiotics, such as Manuka honey and Indian costus. MTB isolates (???? = 15) were evaluated for their susceptibility to Manuka honey graded (...) as +15 and Indian costus by using different concentrations. Among the TB isolates (???? = 15) tested, four (27%) isolates were resistant at 15% v/v honey, while, at 18% v/v of Manuka honey, two (13%) isolates were found to be resistant. Resistance was not seen at honey concentrations of 20% v/v. On the other hand, Indian costus had a slight effectiveness at concentrations of 20% and 25%, affecting only two and five isolates of Mycobacteria, respectively; however, all isolates were inhibited at a concentration of 33% v/v of Indian costus. The present study clearly demonstrates that supposed alternatives (Manuka honey graded as +15 and Indian costus) possess significant anti-mycobacterial activity in vitro; however, further clinical trials should be performed to corroborate our initial findings. (shrink)

In this volume, Maher contextualizes the work of a group of contemporary analytic philosophers—The Pittsburgh School—whose work is characterized by an interest in the history of philosophy and a commitment to normative functionalism, or the insight that to identify something as a manifestation of conceptual capacities is to place it in a space of norms. Wilfrid Sellars claimed that humans are distinctive because they occupy a norm-governed "space of reasons." Along with Sellars, Robert Brandom and John McDowell have tried (...) to work out the implications of that idea for understanding knowledge, thought, norms, language, and intentional action. The aim of this book is to introduce their shared views on those topics, while also charting a few key disputes between them. (shrink)

The idea that plants have minds can sound improbable, but some widely respected contemporary scientists and philosophers find it plausible. It turns out to be rather tricky to vindicate the presumption that plants do not have minds, for doing so requires getting clear about what plants can do and what exactly a mind is. By connecting the most compelling empirical work on plant behavior with philosophical reflection on the concept of minds, _Plant Minds _aims to help non-experts begin to think (...) clearly about whether plants have minds. Relying on current consensus ideas about minds and plants, Chauncey Maher first presents the best case for thinking that plants do _not_ have minds. Along the way, however, he unearths an idea at the root of that case, the idea that having a mind requires the capacity to represent the world. In the last chapter, he defends a relatively new and insightful theory of mind that rejects that assumption, making room for the possibility that plants do have minds, primarily because they are alive. (shrink)

The elevation of ordinary, functional, and task‐based movements were cast as a central aesthetic strategy in the dance concerts at the Judson Memorial Church. A dance ontology focused on an art product could emerge from dance's choreographic structure. A twist to Danto's indiscernibility demands that the performative aspect of the dance medium requires more to capture the aliveness that stilled objects of art do not have.Yvonne Rainer's innovation gives credence to the aliveness in an art capable of always reinventing the (...) ordinary. Aliveness becomes the aboutness of dance. Danto's embodiment amounts to “symbolic expression.” One way Rainer achieved an embodied everydayness was by including artists with no dance training such as Rauschenberg or Morris, or the composer Philip Corner. Dance historian Sally Banes has shown the way Rainer's development of the everyday could be seen as part of a larger investigation. (shrink)

This study aims to use the Asian knowledge model “APO” as a determinant for performance excellence in universities and identifying the most effecting factors on it. This study was applied on Al-Azhar University in Gaza strip. The result of the study showed that (APO) model is valid as a measure and there are four dimensions in the model affecting significantly more than the others (university processes, KM leadership, personnel, KM outputs). Furthermore, performance excellence produced though modernizing the means of education, (...) curriculum development, technology and flexibility in the organizational structure. The study recommends expanding the usage of (APO) model, enhancing the role of knowledge leadership, technology, organizational flexibility, sharing culture and incentive systems that encouraging innovation. (shrink)

Anticolonial theorists and revolutionaries have long turned to dialectical thought as a central weapon in their fight against oppressive structures and conditions. This relationship was never easy, however, as anticolonial thinkers have resisted the historical determinism, teleology, Eurocentrism, and singular emphasis that some Marxisms place on class identity at the expense of race, nation, and popular identity. In recent decades, the conflict between dialectics and postcolonial theory has only deepened. In _Decolonizing Dialectics _George Ciccariello-Maher breaks this impasse by bringing (...) the work of Georges Sorel, Frantz Fanon, and Enrique Dussel together with contemporary Venezuelan politics to formulate a dialectics suited to the struggle against the legacies of colonialism and slavery. This is a decolonized dialectics premised on constant struggle in which progress must be fought for and where the struggles of the wretched of the earth themselves provide the only guarantee of historical motion. (shrink)

Confirmation is commonly identified with positive relevance, E being said to confirm H if and only if E increases the probability of H. Today, analyses of this general kind are usually Bayesian ones that take the relevant probabilities to be subjective. I argue that these subjective Bayesian analyses are irremediably flawed. In their place I propose a relevance analysis that makes confirmation objective and which, I show, avoids the flaws of the subjective analyses. What I am proposing is in some (...) ways a return to Carnap's conception of confirmation, though there are also important differences between my analysis and his. My analysis includes new accounts of what evidence is and of the indexicality of confirmation claims. Finally, I defend my analysis against Achinstein's criticisms of the relevance concept of confirmation. (shrink)

Anticolonial theorists and revolutionaries have long turned to dialectical thought as a central weapon in their fight against oppressive structures and conditions. This relationship was never easy, however, as anticolonial thinkers have resisted the historical determinism, teleology, Eurocentrism, and singular emphasis that some Marxisms place on class identity at the expense of race, nation, and popular identity. In recent decades, the conflict between dialectics and postcolonial theory has only deepened. In _Decolonizing Dialectics _George Ciccariello-Maher breaks this impasse by bringing (...) the work of Georges Sorel, Frantz Fanon, and Enrique Dussel together with contemporary Venezuelan politics to formulate a dialectics suited to the struggle against the legacies of colonialism and slavery. This is a decolonized dialectics premised on constant struggle in which progress must be fought for and where the struggles of the wretched of the earth themselves provide the only guarantee of historical motion. (shrink)

James Joyce's 'Nonpragmatic Vindication of Probabilism' gives a new argument for the conclusion that a person's credences ought to satisfy the laws of probability. The premises of Joyce's argument include six axioms about what counts as an adequate measure of the distance of a credence function from the truth. This paper shows that (a) Joyce's argument for one of these axioms is invalid, (b) his argument for another axiom has a false premise, (c) neither axiom is plausible, and (d) without (...) these implausible axioms Joyce's vindication of probabilism fails. (shrink)

How can formal methods be applied to philosophical problems that involve informal concepts of ordinary language? Carnap answered this question by describing a methodology that he called “explication." Strawson objected that explication changes the subject and does not address the original philosophical problem; this paper shows that Carnap’s response to that objection was inadequate and offers a better response. More recent criticisms of explication by Boniolo and Eagle are shown to rest on misunderstandings of the nature of explication. It is (...) concluded that explication is an appropriate methodology for formal philosophy. (shrink)

This is an essay in the Bayesian theory of how opinions should be revised over time. It begins with a discussion of the principle that van Fraassen has dubbed "Reflection". This principle is not a requirement of rationality; a diachronic Dutch argument, that purports to show the contrary, is fallacious. But under suitable conditions, it is irrational to actually implement shifts in probability that violate Reflection. Conditionalization and probability kinematics are special cases of the principle not to implement shifts that (...) violate Reflection; hence these principles are also requirements of rationality under suitable conditions, though not universal requirements of rationality. (shrink)

The word ‘probability’ in ordinary language has two different senses, here called inductive and physical probability. This paper examines the concept of inductive probability. Attempts to express this concept in other words are shown to be either incorrect or else trivial. In particular, inductive probability is not the same as degree of belief. It is argued that inductive probabilities exist; subjectivist arguments to the contrary are rebutted. Finally, it is argued that inductive probability is an important concept and that it (...) is a mistake to try to replace it with the concept of degree of belief, as is usual today. (shrink)

Hempel's paradox of the ravens arises from the inconsistency of three prima facie plausible principles of confirmation. This paper uses Carnapian inductive logic to (a) identify which of the principles is false, (b) give insight into why this principle is false, and (c) identify a true principle that is sufficiently similar to the false one that failure to distinguish the two might explain why the false principle is prima facie plausible. This solution to the paradox is compared with a variety (...) of other responses and is shown to differ from all of them. (shrink)

A widely endorsed thesis in the philosophy of science holds that if evidence for a hypothesis was not known when the hypothesis was proposed, then that evidence confirms the hypothesis more strongly than would otherwise be the case. The thesis has been thought to be inconsistent with Bayesian confirmation theory, but the arguments offered for that view are fallacious. This paper shows how the special value of prediction can in fact be given Bayesian explanation. The explanation involves consideration of the (...) reliability of the method by which the hypothesis was discovered, and thus reveals an intimate connection between the 'logic of discovery' and confirmation theory. (shrink)

We ask what type of neutralization techniques corporations apply to allegations of human rights abuses. We proceed by undertaking a Qualitative Content Analysis of 162 responses by ten extractives-sector firms over a period of 14 years. The firms were responding to accusations of human rights impacts documented by the Business and Human Rights Resource Centre. We use Garrett et al.’s :507–520, 1989) framework of neutralization techniques consisting of denial, justification, concession and excuse to examine the responses. During our QCA, we (...) observed emerging themes around self-promotion and evasive tactics. We contribute to existing literature by proposing ‘evasion’ as a novel neutralization technique, particularly in circumstances of corporate responses to accusations of wrongdoing. We argue that evasion occurs when firms refuse to engage in the debate brought forward in an accusation. In addition, we enrich our understanding of neutralization techniques by proposing subneutralization techniques in our analysis to diverge from that of other studies. We conclude by discussing the implications of the predominance of corporate narcissism and evasive neutralization techniques to the business and human rights movement and other international corporate responsibility standards. (shrink)

ABSTRACTMany academic authors, policy makers, NGOs, and corporations have focused on top-down human rights global norm-making, such as the United Nations Guiding Principles for Business and Human Rights. What is often missing are contextual and substantive analyses that interrogate rights mobilization and linkages between voluntary transnational rules and domestic governance. Deploying a socio-legal approach and using a combination of longitudinal field and archival data, this article investigates how a local, indigenous community in Northern Chile mobilized their rights over a period (...) of almost two decades. We found that rights mobilization was largely shaped by tensions between the different logics of legality and the business organization. In our case, the UNGP implementation process has been ineffective in giving rightsholders access to genuine remedy. On the contrary, it has led to weakened rights mobilization, dividing the local community. We conclude that greater attention to rights mobilization and domestic governance dynamics should be given in the business and human rights debate. (shrink)

Recently a number of authors have tried to avoid the failures of traditional Dutch book arguments by separating them from pragmatic concerns of avoiding a sure loss. In this paper I examine defenses of this kind by Howson and Urbach, Hellman, and Christensen. I construct rigorous explications of their arguments and show that they are not cogent. I advocate abandoning Dutch book arguments in favor of a representation theorem.

This article theorises the contemporary convergence of neoliberal and fascist principles by examining the thought of political actors in the 1930s and 1940s who were active in both neoliberal and fascist organisations. I suggest that a sympathy for fascism formed a minor but significant strand of early neoliberal thought, and that unpacking the logics that led particular thinkers and political actors to believe that fascism was compatible with neoliberalism can shed light on the contemporary political moment. Based on my reading (...) of early ‘neoliberal fascists’, I theorise three points of convergence. The first was a belief that socialism had to be opposed by all possible means, including violence and the repression of popular democracy. The second was a racialized understanding of the underpinnings of the market economy, leading to an acceptance of the necessity of racial exclusion. Thirdly, both fascist and neoliberal thinkers believed that patriarchy was a necessary feature for the reproduction of capitalism, and hence that traditional gender roles had to be preserved against pressures for social change. In theorising this convergence, I also gesture to how the overlap of neoliberalism and fascism can be witnessed in the contemporary milieu, with a focus on the libertarian Mises Institute. (shrink)

This chapter examines whether we can know that plants are or are not conscious. We consider a recent debate between an optimistic view, which holds that plants might be conscious, and a pessimistic view, which denies that current evidence supports this claim. The optimistic position appeals to similarities between plants and conscious animals, noting that plants exhibit adaptive, flexible, and goal-directed behaviors such as communication, learning, and anticipatory responses. The pessimistic response argues that these similarities are either misleading or irrelevant, (...) since such behaviors can be explained as forms of adaptive responsiveness and do not indicate consciousness. It also emphasizes that plants lack features, such as nervous systems, that are commonly associated with consciousness. We conclude that the pessimistic position appears stronger: there are no good grounds for thinking that plants are conscious. However, we urge caution in concluding that we know they are not. Our current understanding of consciousness remains limited, and we lack a well-supported account of why particular biological features are necessary for it. In the absence of such a theory, claims about plant consciousness remain uncertain. (shrink)

This article analyses the ethics of how community engagement and dialogue as applied by a mining corporation in Chile led to erosion of the community’s psychological freedom despite being aligned with best practice. This article details how a mining company squeezed the psychological freedom of the community in order to obtain an agreement between the period of 2000 and 2016. The findings focus particularly on a 9-month period between 2015 and 2016 when the company undertook intense community engagement. The article (...) identifies six corporate action phases undertaken which curtailed the community’s psychological freedom as paying off local leaders; challenging via courts of law; co-opting community lawyers; prohibiting a key debate during dialogue; and remaining silent after failing to honour its own self-imposed rule. The findings label the company’s community engagement as contradictory; while it conducted transitional and transformational engagement in formal spaces, it also engaged in unethical strategies in the informal spaces of community engagement. The result was overall community consent and an even more fragmented community. This article finds that when it limits the psychological freedom of participants, who are already divided as a group, corporate–community engagement can be viewed as ethically problematic. Based on analysis of the literature and an empirical case analysis, this article contributes a test for assessing the ethics of CCE. (shrink)

Let R(X, B) denote the class of probability functions that are defined on algebra X and that represent rationally permissible degrees of certainty for a person whose total relevant background evidence is B. This paper is concerned with characterizing R(X, B) for the case in whichX is an algebra of propositions involving two properties and B is empty. It proposes necessary conditions for a probability function to be in R(X, B), some of which involve the notion of statistical dependence. The (...) class of probability functions that satisfy these conditions, here denoted PI, includes a class that Carnap once proposed for the same situation. Probability functions in PI violate Carnap's axiom of analogy but, it is argued, that axiom should be rejected. A derivation of Carnap's model by Hesse has limitations that are not present in the derivation of PI given here. Various alternative probability models are considered and rejected. (shrink)

Inductive probability is the logical concept of probability in ordinary language. It is vague but it can be explicated by defining a clear and precise concept that can serve some of the same purposes. This paper presents a general method for doing such an explication and then a particular explication due to Carnap. Common criticisms of Carnap's inductive logic are examined; it is shown that most of them are spurious and the others are not fundamental.

Using the political corporate social responsibility lens of parentalism, this paper investigates the more subtle and less-visible interactional dynamics and strategies of power, resistance and justification that manifest between a multi-stakeholder-governed foundation and victims of a mining corporation’s dam collapse. The Renova Foundation was established to provide remedy through a deliberative approach to hundreds of thousands of victims from Brazil’s worst socio-environmental disaster—the collapse of Samarco Mining Corporation’s Fundão tailings dam. Data were collected from a combination of fieldwork and archival (...) analysis to assess the perceptions of victims, their defenders and foundation executives. The findings reveal 12 dialectical tensions from Renova’s attempts to remedy the victim’s injustices. The case analysis contributes through proposing a dialectical process model of stakeholder resistance and subversion to parentalist PCSR. The case reveals the pivotal use of time via the act of stalling as a strategic resource to exhaust victims and reach settlements. Furthermore, organizations justify their parentalism by blaming delays on the bureaucracy and shared responsibility of multi-stakeholder deliberation. Ultimately, I contend that victims must have an equal voice in the outcome of their remediation and that businesses responsible for causing harm should not decide these matters. (shrink)

Evidence for a hypothesis typically confirms the hypothesis more if the evidence was predicted than if it was accommodated. Or so I argued in previous papers, where I also developed an analysis of why this should be so. But this was all a mistake if Howson and Franklin (1991) are to be believed. In this paper, I show why they are not to be believed. I also identify a grain of truth that may have been dimly grasped by those Bayesians (...) who deny the confirmatory value of prediction. (shrink)

Disillusionment is acknowledged to be a painful process with important personal and social consequences. However, scientific conceptualisations of the experience are inconsistent. Across four studies, we examined whether lay conceptions of disillusionment produce a consistent pattern of features. In Study 1 (N = 204), we extracted 19 features of disillusionment from open-ended participant definitions. In Study 2 (N = 131), participants rated the centrality of these features and indicated that features such as discovery, disappointment, and loss, were highly representative, while (...) features such as hopelessness, orientation, and truth, were more peripheral. In two further studies, we used experimental designs to test the diagnosticity of these features. In Study 3 (N = 155), participants rated vignettes descriptions as more disillusioning when they were based on more, rather than less, prototypical disillusionment features. Given that disappointment is a feature of disillusionment, we conducted Study 4 (N = 60) to test whether the extracted features effectively distinguish disillusionment from disappointment. Overall, we found evidence to suggest that disillusionment contains a consistent set of features, and represents a state of negative epistemic affect associated with the violation of core assumptions. These results create avenues for research on disillusionment, its antecedents and its consequences. (shrink)

Uttered language does not necessarily reflect the planned communications of schizophrenia patients, nor do their delusions necessarily reflect basic failures of inferential reasoning. The role of inhibitory failure in the production of speech and the role of primary experiences of discrepancy between intention and action, and between experience–based expectations and perceived realities account for many of the clinical phenomena that have led to the conclusion that these patients have a ‘thought’ disorder, or a ‘disturbed’ mind. The alternatives and the evidence (...) are summarized in this paper. (shrink)

In his Responsibility and the moral sentiments , Wallace develops the idea that we should think of what it is to be morally responsible for an act in terms of norms for holding someone responsible for that act. Smith has recently claimed that Wallace's approach and those like it are 'fundamentally misguided'. She says that such approaches make the mistake of incorporating conditions for 'actively blaming' others into the basic conditions for being responsible, when in fact the conditions for active (...) blame 'go beyond' the basic conditions. In this essay, I argue that Smith's otherwise illuminating discussion of these 'Normativist' approaches does not undermine them. Specifically, I maintain that being actively blamable by certain persons with the relevant standing is actually constitutive of being responsible for at least some acts. By distinguishing between persons with different sorts of standing, a Normativist approach can avoid Smith's challenge. My larger aim is thus to clarify and defend the Normativist approach. (shrink)

Hi‘ilei Julia Kawehipuaakahaopulani Hobart and Tamara Kneese (2020) define radical care as ‘as a set of vital but underappreciated strategies for enduring precarious worlds’ (16). Yet they sound a note of caution when they argue that ‘because radical care is inseparable from systemic inequality and power structures, it can be used to coerce subjects into new forms of surveillance and unpaid labor’ (16). This article explores scaffolded peer-to-peer programmes as a form of radical care. In these programmes and approaches people (...) are connected in non-hierarchical structures of mutual support and care that locate lived experience, rather than solely professional accreditation, as powerful, inclusive and collaborative expertise. The often implicit and traditional hierarchies of care are challenged in this structuring; we argue that the dynamic and horizontal structure of peer care practices can subvert and ultimately enrich circulating discourses of self-care, commodified care and the neoliberal devolution of responsibility for health and well-being to individuals. (shrink)

In October 2009 I decided to stop doing philosophy. This meant, in particular, stopping work on the book that I was writing on the nature of probability. At that time, I had no intention of making my unfinished draft available to others. However, I recently noticed how many people are reading the lecture notes and articles on my web site. Since this draft book contains some important improvements on those materials, I decided to make it available to anyone who wants (...) to read it. That is what you have in front of you. The account of Laplace’s theory of probability in Chapter 4 is very different to what I said in my seminar lectures, and also very different to any other account I have seen; it is based on a reading of important texts by Laplace that appear not to have been read by other commentators. The discussion of von Mises’ theory in Chapter 7 is also new, though perhaps less revolutionary. And the final chapter is a new attempt to come to grips with the popular, but amorphous, subjective theory of probability. The material in the other chapters has mostly appeared in previous articles of mine but things are sometimes expressed differently here. I would like to say again that this is an incomplete draft of a book, not the book I would have written if I had decided to finish it. It no doubt contains poor expressions, it may contain some errors or inconsistencies, and it doesn’t cover all the theories that I originally intended to discuss. Apart from this preface, I have done no work on the book since October 2009. (shrink)

Van Fraassen has maintained that acceptance of a scientific theory does not involve the belief that the theory is true. Blackburn, Mitchell and Horwich have claimed that acceptance, as understood by van Fraassen, is the same as belief; in which case, van Fraassen's position is incoherent. Van Fraassen identifies belief with subjective probability, so the question at issue is really whether acceptance of a theory involves a high subjective probability for the theory. Van Fraassen is not committed to this, and (...) hence the charge of incoherence is misplaced. Indeed, van Fraassen is correct on this point. However, he is wrong to think that acceptance requires a high subjective probability that the theory is empirically adequate; and his reason for thinking that science aims at empirical adequacy rather than truth rests on an overly crude theory of rational choice. (shrink)

A "symptomatic act" is an act that is evidence for a state that it has no tendency to cause. In this paper I show that when the evidential value of a symptomatic act might influence subsequent choices, causal decision theory may initially recommend against its own use for those subsequent choices. And if one knows that one will nevertheless use causal decision theory to make those subsequent choices, causal decision theory may favor the one-box solution in Newcomb's problem, and may (...) recommend against making cost-free observations. But if one can control one's future choices, then causal decision theory never recommends against cost-free observation. (shrink)

Maher, Anthony Review of: Transforming theology: Student experience and transformative learning in undergraduate theological education, by Les Ball ISBN 9781743240298, pp.177, pb, $44.95.